Over time, several studies have demonstrated that finasteride is a safe and well-tolerated drug, with rare and reversible side effects such as reduced sexual libido and ejaculatory volume, most commonly observed when prescribed in 150mg/ day transdermal Testosterone gel applied to scrotum - 50mg/ day DHT gel applied to inner forearms and penis - 50mg oral pregnenolone/25mg DHEA daily, https://old.reddit.com/r/FinasterideSyndrome/comments/u1svwo/has_anyone_else_recovered_from_watery_semen_and/i4eg1it/?context=999. To diagnose retrograde ejaculation, your doctor may: If you have dry orgasms, but your doctor doesn't find semen in your bladder, you might have a problem with semen production. I am 100% reversed Keep in mind if I miss a dose or stop my protocol Pfs comes back full force. I did a cycle of hcg 250ui m/w/f for 6 months + a week and a half of clomid 25 everyday + DHEA (I know I'm a idiot) More or less cured me from no low libido and all that great stuff for over a year now and I'm off everything. Management of the dry ejaculate: A systematic review of aspermia and retrograde ejaculation. While most men can get their female partners pregnant with infertility treatment, it can be costly and require stressful medical procedures for both you and your partner. It is available as a generic. However, the side effects of a medication usually go away when you stop taking it. For details, see text. Disclaimer. I could be wrong but none of them seem to have anhedonia or genital numbness or fatigue or insomnia or anything, just libido and ED issues. Epub 2022 Feb 3. It can cause bladder and urination problems. They kept saying it was on the verge of having a major announcement 2 YEARS ago. Hello, some finasteride users have reported the reversal of post-finasteride syndrome using HCG as therapy. Crazy. Stopping finasteride treatment can cause post-finasteride syndrome. This may result in side effects such as memory problems or sexual dysfunction (problems that affect the desire for or ability to have sex). Post-finasteride syndrome wasnt reported in clinical studies, but it has been reported since the drug was approved. Plentiful in opinions, short on facts. His article with all the studies hes referencing: Post Finasteride Syndrome can be manually corrected by interpreting blood work and implementing an appropriate lifestyle and/or pharmacological protocol. You're right. I'll never be without this stuff again. https://old.reddit.com/r/steroids/comments/m5m7o9/help_steroids_for_pssd/gr0uhqj/. Bookshelf Would you like email updates of new search results? This site needs JavaScript to work properly. Here's some information to help you get ready for your appointment, and what to expect from your doctor. Diagnosing and Reversing It", Is Post Finasteride Syndrome Real? PLUS, the latest news on medical advances and breakthroughs from Harvard Medical School experts. Get helpful tips and guidance for everything from fighting inflammation to finding the best diets for weight lossfrom exercises to build a stronger core to advice on treating cataracts. Brain fog. Adverse side effects of 5-reductase inhibitors therapy: persistent diminished libido and erectile dysfunction and depression in a subset of patients. In addition, it has been also reported that persistent side effects may occur in some AGA patients. For details,, MeSH The dosage needs to be low and steady, do not increase or add a day thinking more is better. I'm not going to go into the entire history of what post finasteride syndrome is, and I assume many of you looking into buying Tribulus know exactly what it is. Am I at risk of complications from this condition? As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Serious Side Effects: Post Finasteride Syndrome This procedure is usually done at the doctor's office. What websites do you recommend visiting? To be honest, I think for the most part these recoveries werent PFS but rather hormonal imbalances. A community dedicated to people suffering long term effects after taking 5-ar inhibitors such as Propecia/Finasteride, or for people who wish to know more about the constellation of symptoms commonly known as Post Finasteride Syndrome. Chicago Man: Taking Propecia is the Biggest Regret lol. I had all the classic symptoms. I also started a thread but they merged it. Recovered from Post Finasteride Syndrome! : r/tressless Yeah, yeah. Is there a generic alternative to the medicine you're prescribing me? Now I can happily say that I no longer have any problem, strong erection all day and all night. WTF. This is not proof that finasteride is to blame, since a variety of medical conditions and other prescription drugs could explain the sexual symptoms. Btw, something weird happening on propeciahelp forums. -. Will my partner and I likely need to use assisted reproductive technology, such as intrauterine insemination, to achieve pregnancy? Some people had to use anabolic steroids because herbs weren't strong enough. Sign up to get tips for living a healthy lifestyle, with ways to fight inflammation and improve cognitive health, plus the latest advances in preventative medicine, diet and exercise, pain relief, blood pressure and cholesterol management, andmore. The symptoms of PFS start to subside within four to eight months after discontinuing the medicine. I only said everyone should read it, especially in light of the big new proviron recovery on the forum there. Finasteride oral tablet side effects: How to manage them As here reported, these observations are mainly based on self-reporting of the symptomatology by the patients and few clinical studies have been performed so far. The management of retrograde ejaculation: A systematic review and update. ._1x9diBHPBP-hL1JiwUwJ5J{font-size:14px;font-weight:500;line-height:18px;color:#ff585b;padding-left:3px;padding-right:24px}._2B0OHMLKb9TXNdd9g5Ere-,._1xKxnscCn2PjBiXhorZef4{height:16px;padding-right:4px;vertical-align:top}.icon._1LLqoNXrOsaIkMtOuTBmO5{height:20px;vertical-align:middle;padding-right:8px}.QB2Yrr8uihZVRhvwrKuMS{height:18px;padding-right:8px;vertical-align:top}._3w_KK8BUvCMkCPWZVsZQn0{font-size:14px;font-weight:500;line-height:18px;color:var(--newCommunityTheme-actionIcon)}._3w_KK8BUvCMkCPWZVsZQn0 ._1LLqoNXrOsaIkMtOuTBmO5,._3w_KK8BUvCMkCPWZVsZQn0 ._2B0OHMLKb9TXNdd9g5Ere-,._3w_KK8BUvCMkCPWZVsZQn0 ._1xKxnscCn2PjBiXhorZef4,._3w_KK8BUvCMkCPWZVsZQn0 .QB2Yrr8uihZVRhvwrKuMS{fill:var(--newCommunityTheme-actionIcon)} Examine your urine for the presence of semen after you have an orgasm. Very controversial topic in this forum. If I do achieve an erection it has to be constantly stimulated or it goes away FAST and even thats not a guarantee. After stopping 7 weeks later (when I ran out of my proviron), things felt off for a few weeks but then after around two months I got back to my pre-PFS state. Im talking about the physical inability to have erections and sex drive". Bethesda, MD 20894, Web Policies Incredible! I have the desire for sex and intimacy but my brain simply wont communicate with my penis when its time for intercourse. Retrograde ejaculation can be especially challenging if you and your partner want to conceive a child. I read about the Post-Fin Syndrome and decided to quit (Almost) No erections, no libido. Almost starting to think like a conspiracy theorist. Post-Finasteride Syndrome: Current Views and Where do we Stand? I took 2 capsules before my daily workout at around 6pm and another 4 capsules 20 minutes before bedtime. I am not aware of the use of Human Growth Hormone in the treatment for Post Finasteride Syndrome. You can't get worse than living with no dick dude. All rights reserved. Keywords: Epub 2013 Jul 24. more https://www.jasonemermd.com/cosmetic-dermatology/regenerative-medicine/hormonal 2019;38:762774. Finasteride oral tablet Disorders of male orgasm and ejaculation. And yeah I know hackstasis, looks to be a much better community and forum than propeciahelp without fascist mods. Chlorpheniramine and brompheniramine, antihistamines that help relieve allergies. Traish AM, Hassani J, Guay AT, Zitzmann M, Hansen ML. Mods are always talking about the survey too, I said a survey wont cure us and we could be be waiting for 10 years if we dont do anything. Effect of 5-Reductase Inhibitors on Sexual Function: A Meta-Analysis and Systematic Review of Randomized Controlled Trials. My doctor put me on 5mg daily cialis (+up to 15mg as needed before sex) clomiphene 25mg/daily anastrozole 1mg/week Addyi shockwave therapy ($3000 for 6 sessions) though this is definitely unnecessary and experimental. However, minoxidil is used "off-label" for treating telogen effluvium, scarring alopecia and alopecia areata. Getting to the root cause of your hairloss would be the first thing to do as if you have an underlying medical condition, once thats treated, it could reverse the hairloss, so definately get a consultation with a physician to rule out anything treatable. Common finasteride side effects include loss of libido, breast enlargement, erectile dysfunction (ED), and lower ejaculatory volume. This area was the most recovery and reversal of symptoms. I have had a recent report of a man who went on Human Growth Hormone and reversed his post finasteride syndrome sexual dysfunction. Authors received funding from the Post-Finasteride Foundation in order to study PFS symptomatology of patients and in experimental models. That fog, that mental barrier that kept me feeling a distance from myself had totally lifted. WebI cannot say enough about this. Therefore, understand that I can't promise this will work for youbut for me? And posted the article and some cliffs about his solution. Im on HCG now too though so who knows, maybe itll help too, Powered by Discourse, best viewed with JavaScript enabled, Video: "Is Post Finasteride Syndrome Real? Look, it's as simple as this. The results have been amazing and far too great to chalk it up to just being a placebo. Your doctor will want to determine whether your dry orgasms are retrograde ejaculation or linked to another problem that may need further evaluation. Instead of having a discussion, nope banned. Key takeaways: Finasteride is an FDA-approved medication that treats hair loss in men. Make a donation. Day 1 I felt no difference. Its H.C.G (HCG) dosed at 250IU Monday, Wednesday and Friday only. Finasteride causes cognitive & sexual decline. Last time I was on there they had started discussing some relationships between HCG and Thyroid? doi: 10.1177/0960327119842195. Urology. I didnt feel any improvement and felt worse during that period but after that period I healed which is very weird. Epub 2010 Dec 22. Press J to jump to the feed. post-finasteride syndrome Since your question stresses on age and since there might be other young people in their 20s and 30s who might find this question and come looking for answers, I thought I might start by pointing that out. Ive seen many others who give their opinion but are banned as a result. When did you first begin having dry orgasms? @keyframes ibDwUVR1CAykturOgqOS5{0%{transform:rotate(0deg)}to{transform:rotate(1turn)}}._3LwT7hgGcSjmJ7ng7drAuq{--sizePx:0;font-size:4px;position:relative;text-indent:-9999em;border-radius:50%;border:4px solid var(--newCommunityTheme-bodyTextAlpha20);border-left-color:var(--newCommunityTheme-body);transform:translateZ(0);animation:ibDwUVR1CAykturOgqOS5 1.1s linear infinite}._3LwT7hgGcSjmJ7ng7drAuq,._3LwT7hgGcSjmJ7ng7drAuq:after{width:var(--sizePx);height:var(--sizePx)}._3LwT7hgGcSjmJ7ng7drAuq:after{border-radius:50%}._3LwT7hgGcSjmJ7ng7drAuq._2qr28EeyPvBWAsPKl-KuWN{margin:0 auto} Careers. I suggest you see an expert for internal workup, we do this frequently in our practice. Stay on top of latest health news from Harvard Medical School. The presence of side effects during pharmacological treatment is unfortunately a quite common problem. 5alpha-reductase; Androgenetic alopecia; Depression; Finasteride; Neuroactive steroids; Sexual dysfunction. Not orgasm strength and sperm levels have returned, just waiting on my brain to communicate with my penis when its time for sexual intercourse. The steroidogenic inhibitor finasteride reverses pramipexole-induced alterations in probability discounting. Samplaski MK, et al. 2008;35:211. official website and that any information you provide is encrypted The number of men sharing their experience of Post-Finasteride Syndrome is steadily rising, painting a bleak picture of the life-shattering effects the drug can have. Plus, get a FREE copy of the Best Diets for Cognitive Fitness. Your doctor might ask: Mayo Clinic does not endorse companies or products. Anejaculation and retrograde ejaculation. Its on an auto refill and I get 90 day supplies sent to me in the mail. Advertising revenue supports our not-for-profit mission. .FIYolDqalszTnjjNfThfT{max-width:256px;white-space:normal;text-align:center} Unable to load your collection due to an error, Unable to load your delegates due to an error. Its easy to point to a little blue pill you took 10 years ago than to look for other causes. At higher doses, finasteride (Proscar) can also treat benign prostatic hyperplasia (BPH). and transmitted securely. WebIn addition to the sexual, mental and physical side effects, PK suffers from miscellaneous issues connected with PFS. Male pattern baldness develops when DHT binds to receptors in the scalp and causes the hair follicles to miniaturize. Diviccaro S, Giatti S, Cioffi L, Falvo E, Herian M, Caruso D, Melcangi RC. Answer: Hormonal optimization while on finesteride there are many options including peptides, and HCG as well as clomid/arimidex. breast tenderness. Fertility and Sterility. When seeing your doctor for dry ejaculation the primary sign of retrograde ejaculation some basic questions to ask your doctor include: If you're trying to get your female partner pregnant, you might also want to ask: In addition to the questions that you've prepared to ask your doctor, don't hesitate to ask additional questions during your appointment. Are there any brochures or other printed material that I can take home with me? Clinical features reported in patients affected by post-finasteride syndrome. In addition, molecular mechanisms and/or genetic determinants behind such adverse effects have been poorly explored both in patients and animal models. Ask questions about your symptoms and how long you've had them. Yeah the joe_kool guy or whatever his name is had really good luck with TRT, he is honestly the reason I went down this road. The common denominator in how I feel is Tribulus, period, end of sentence. This after having PFS constantly for 11 years. Post Finasteride Syndrome Real? Diagnosing WebPost-finasteride syndrome occurs in men whove taken finasteride to treat hair loss or enlarged prostates. Metab. Ferri FF. 2022 Oct 26;12(11):1567. doi: 10.3390/biom12111567. That is 250IU, not a typo so youll mix your 5000iu HCG with 5CC water and take 1/4 CC intramuscular three times a week using an insulin needle Have you heard about it? What medications or herbal remedies do you take? Metabolism of progesterone and testosterone, Metabolism of progesterone and testosterone into 5alpha-reduced metabolites and their mechanisms of action:, Clinical features reported in patients affected by post-finasteride syndrome. Day 2 I noticed a bit more energy, but credited that to having a good night's sleep (did I mention this stuff helps you sleep better, too?) How much worse can it get then being a lifeless piece of flesh that hasnt been erect or had any kind of sensation in months and months? BONUS! Please visit the wiki for published research, symptoms, and more. Stop watching porn, stop masturbating, forget about sex, meditate, take cold showers, try breathing exercises, try extended water fasting. I read the thing on Healthline where it says it doesn't raise testosterone in humans. Finasteride They claim its more to cover their ass because they dont want people trying whatever unproven solution and get worse and commit suicide or something. 2019;16 doi: 10.3390/ijerph16101726. I also tried testosterone treatment but it had almost no effect regardless of dosage. However, careful selection of patients and monitoring the finasteride treatment may prevent the PFS to some extent. Before Proviron saved my life. In this review, we focused our attention on adverse events related to 5 alpha-reductase (5-R) inhibitors (i.e., finasteride and dutasteride), approved for the treatment of benign prostatic hyperplasia and androgenetic alopecia (AGA). 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). In some people with PFS, DHT might be normal, but testosterone and cortisol low and estrogen and prolactin high. Can sperm be retrieved from my bladder and used for fertility treatment? 2015;12:401. Traish AM, Melcangi RC, Bortolato M, Garcia-Segura LM, Zitzmann M. Rev Endocr Metab Disord. Its like they want to hide possible solutions. Pornography usually has to be in the picture but there are RARE times when I get a spontaneous boner I can play with that will stick around and I can achieve orgasm with or without pornography. I have not made any drastic life changes since beginning this. Therefore, I cut the pills in half (2.5mg) and toss the other half. If so, how long have you been trying to conceive? These hippocampal neurogenesis changes after finasteride treatment have been linked to emotional behavior and this might contribute to the pathophysiology of affective disorders in humans. -, Baas W.R., Butcher M.J., Lwin A., Holland B., Herberts M., Clemons J., Delfino K., Althof S., Kohler T.S., McVary K.T. You're likely to start by seeing your family doctor. Post Finasteride Syndrome Recovery - YouTube Thanks for visiting. Finasteride blocks the metabolism of testosterone. 2015 Sep;16(3):177-98. doi: 10.1007/s11154-015-9319-y. Most men eventually develop some type of prostate problem, and when they do there are usually no easy solutions. I just decided to get back on gear after a year off + dutasteride during that time. An official website of the United States government. For what it's worth, here's a couple similar success stories involving numbness, but from PSSD instead of PFS: Testosterone along with initial estrogen management , completely cured my pssd, everything from numbness, to hard on quality , no morning wood, to actually having sexual desires again. Took finasteride for 5 months. To give you a bit of background, I'm a 34 year old male whose sexual function was utterly destroyed by finasteride/Propecia. 2013 Oct;10(10):2598-603. doi: 10.1111/jsm.12269. This content does not have an Arabic version. Fertility and Sterility. My life is finally back. All of that changed in three days. Elsevier; 2021. https://www.clinicalkey.com. Hcg I did 3000iu the first day then 250iu every other day for the four weeks. Like I said, almost starting to believe they want people to keep having pfs so they can benefit in some form or another. In this review, we focused our attention on adverse events related to 5 alpha-reductase (5-R) inhibitors (i.e., finasteride and dutasteride), approved for the treatment of benign prostatic hyperplasia and androgenetic alopecia (AGA). I know it's been a LONG time and also want to tell everyone that I'm cured from PFS great news. ._12xlue8dQ1odPw1J81FIGQ{display:inline-block;vertical-align:middle} Q. I have heard that finasteride, which I take for my prostate problem, can cause permanent impotence. Elsevier; 2022. https://www.clinicalkey.com. The .gov means its official. Contemporary management of disorders of male orgasm and ejaculation. AR: androgen receptor; CSF: cerebrospinal fluid; MRI: magnetic resonance imaging; SRD5A2: 5 alpha reductase type 2 gene. Were on our own to beat this, just wait is the worst solution to pfs there is. Firstly, hair loss doesn't just affect older people. Toxicol. After taking 50mg of Proviron I got my first erection in years. ._2cHgYGbfV9EZMSThqLt2tx{margin-bottom:16px;border-radius:4px}._3Q7WCNdCi77r0_CKPoDSFY{width:75%;height:24px}._2wgLWvNKnhoJX3DUVT_3F-,._3Q7WCNdCi77r0_CKPoDSFY{background:var(--newCommunityTheme-field);background-size:200%;margin-bottom:16px;border-radius:4px}._2wgLWvNKnhoJX3DUVT_3F-{width:100%;height:46px} I was one of the lucky guys who recovered from Test injections, https://old.reddit.com/r/steroids/comments/igyd61/offtopic_daily_chat_20200826/g2ym80n/. Jefferys A, et al. https://www.isarms.com/forums/threads/post-finasteride-syndrome.18175/. 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